| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-S1PR4 (C-Term) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
S1PR4 |
| Gene ID: |
8698 |
| Uniprot ID: |
S1PR4_HUMAN |
| Immunogen Region: |
C-Term |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human S1PR4 (NP_003766.1). |
| Immunogen Sequence: |
SAVNPIIYSFRSREVCRAVL SFLCCGCLRLGMRGPGDCLA RAVEAHSGASTTDSSLRPRD SFRGSRSLSFRMREPLSSIS SVRSI |
| Tissue Specificity | Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung. |
| Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes. |
| Protein Name | Sphingosine 1-Phosphate Receptor 4S1p Receptor 4S1p4Endothelial Differentiation G-Protein Coupled Receptor 6Sphingosine 1-Phosphate Receptor Edg-6S1p Receptor Edg-6 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-419408 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingosine 1-Phosphate Receptor 4 antibodyAnti-S1p Receptor 4 antibodyAnti-S1p4 antibodyAnti-Endothelial Differentiation G-Protein Coupled Receptor 6 antibodyAnti-Sphingosine 1-Phosphate Receptor Edg-6 antibodyAnti-S1p Receptor Edg-6 antibodyAnti-S1PR4 antibodyAnti-EDG6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
