Anti-SPARC antibody

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Product name Anti-SPARC antibody
Short Description Rabbit polyclonal against SPARC
Description Rabbit polyclonal to SPARC.
Applications ELISA, IHC-p, WB
Dilution range WB 1:500-1:2000
IHC-p 1:100-1:300
ELISA 1:20000
Specificity SPARC polyclonal antibody detects endogenous levels of SPARC protein.
Protein Name Sparc
Basement-Membrane Protein 40
Bm-40
Osteonectin
On
Secreted Protein Acidic And Rich In Cysteine
Immunogen Synthesized peptide derived from human SPARC.
Immunogen Region 141-190 aa, Internal
Storage Instruction Store at-20°C, and avoid repeat freeze-thaw cycles.
Note FOR RESEARCH USE ONLY (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 6678
Gene Symbol SPARC
Database Links HGNC:11219
OMIM:182120
Alternative Names Anti-Sparc antibody
Anti-Basement-Membrane Protein 40 antibody
Anti-Bm-40 antibody
Anti-Osteonectin antibody
Anti-On antibody
Anti-Secreted Protein Acidic And Rich In Cysteine antibody
Anti-SPARC ON antibody
Function Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites.an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
Cellular Localization Secreted
Extracellular Space
Extracellular Matrix
Basement Membrane
In Or Around The Basement Membrane
Swiss-Prot Key SPRC_HUMAN
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