| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SUCLG1 (41-346) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SUCLG1 |
| Gene ID: |
8802 |
| Uniprot ID: |
SUCA_HUMAN |
| Immunogen Region: |
41-346 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 41-346 of human SUCLG1 (NP_003840.2). |
| Immunogen Sequence: |
CSYTASRQHLYVDKNTKIIC QGFTGKQGTFHSQQALEYGT KLVGGTTPGKGGQTHLGLPV FNTVKEAKEQTGATASVIYV PPPFAAAAINEAIEAEIPLV VCITEGIPQQDMVRVKHKLL RQEKTRLIGPNCPGVINPGE CKIGIMPGHIHKKGRIGIVS RSGTLTYEAVHQTTQVGLGQ SLCVGIGGDPFNGTDFIDCL EIFLNDSATEGIILIGEIGG NAEENAAEFLKQHNSGPNS |
| Function | Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. |
| Protein Name | Succinate--Coa Ligase Adp/Gdp-Forming Subunit Alpha - MitochondrialSuccinyl-Coa Synthetase Subunit AlphaScs-Alpha |
| Database Links | Reactome: R-HSA-71403 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Succinate--Coa Ligase Adp/Gdp-Forming Subunit Alpha - Mitochondrial antibodyAnti-Succinyl-Coa Synthetase Subunit Alpha antibodyAnti-Scs-Alpha antibodyAnti-SUCLG1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and CDK7 knockout (KO) 293T cells, using [KO Validated] CDK7 Rabbit polyclonal antibody (STJ114808) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/93895/375110/STJ114808_1__03809.1713141794.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CDK7 knockout (KO) 293T cells, using [KO Validated] CDK7 Rabbit polyclonal antibody (STJ114808) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.")